GDR Micro Nano Fluidique

Mois : février 2016

Phagocytosis by macrophages represents a fundamental process essential for both immunity and tissue homeostasis. Most of our current quantitative knowledge on phagocytosis is based on the use of solid polymer microparticles as model targets that are well adapted to the study of phagocytosis mechanisms that do not involve any lateral mobility of the ligands, despite the relevance of this parameter in the immunological context.

More informations : ANR_OpenPosition (1)

The position is opened in the framework of a prospective joint team on bioengineering between Ecole Polytechnique and Institut Pasteur in Paris. Candidates must have demonstrated excellence in research and teaching and should have a strong interest in teaching mechanics at both the undergraduate and graduate levels.

More details : MECA-MdC-RESIDENT-MICROFLUIDIQUE-GB-1 (1)

Indeed AM process should supplant traditional machining technics quite soon, using a material structuration and deposition, layer-by-layer with the capability to make complex 3D objects without the need for molds, tools or dies of any kind. Just like deposition technologies are becoming more and more efficient for accurate and fast complex objects manufacture, material synthesis/ structuration, currently focused on which a lot of research efforts, turns out to be the key of next innovations.

More information : Post doc position in Limoges

MEPPOT (Personalized medicine, pharmacogenomics and therapeutic optimization, UMRS1147) hosting the recruiting team has an interdisciplinary culture and strong links with the Georges Pompidou European hospital (hEGP) as well as other hospital in Paris. It is hosting the CARPEM (Cancer research for personalized medicine) network allowing strong links with oncologists and clinicians.

More informations : Offrepost doc microfluidic 2016

Prises de responsabilités attendues : On attend de la part du/de la candidat(e) recruté(e) une prise de responsabilités dans les formations, et une implication forte au niveau du département de mécanique fondamentale.

Thèmes de recherche : Le/La candidat(e) recruté(e) proposera un projet scientifique s’inscrivant dans les objectifs de l’Institut d’Electronique, Microélectronique et de Nanotechnologie (IEMN-UMR 8520) et en cohérence avec les orientations scientifiques des départements « Micro et Nano-Systèmes » et « Acoustique » de l’IEMN et de son Laboratoire International Associé LEMAC/LICS. Le laboratoire IEMN souhaite recruter un/une professeur sur des thématiques de recherche à l’interface entre l’acoustique et la microfluidique en vue de leur application à la conception de microsystèmes innovants. Il est attendu que le/la professeur recruté(e) développe une activité expérimentale et de modélisation autour de l’interaction aux échelles micrométriques entre des ondes acoustiques et des fluides complexes. Le contexte très international du laboratoire d’accueil requiert un goût indispensable pour le travail en équipe et les collaborations internationales. Le laboratoire recherche donc un/une professeur qui jouera pleinement son rôle d’animateur/animatrice scientifique dans ce domaine.

Plus de détails : 45071_MATHS_60_PR_787_IEMN

A geometry of particular interest concerns flows in a Hele-Shaw cell, i.e. a channel whose depth is much smaller than its width and length. This classical problem has been studied in depth, both theoretically and experimentally [2-4]. While the theoretical solutions predict that the relative velocity of an inviscid bubble should be twice the velocity of the outer fluid, this is never observed in practice. Instead, bubbles travel at lower speeds than the outer fluid. Moreover, complex recirculation patterns are observed for bubbles rising in a quiescent outer fluid [5]. All of these observations point to the effect of an uneven surfactant coverage of the interface and its redistribution due to the fluid motion.

More informations : PostdoctoralPositionLIONS

The goal of this project is to design and set-up a microfluidic device that mimics the characteristics of a blood microcirculation network. Capillaries are watertight conduits lined with endothelial cells surrounded by extracellular matrix with a 10 µm-wide lumenand organize in complex networks. These small vessels are submitted to various biophysical stimuli such as shear stress, pressure or oxygen concentration. In addition, different cell types such as pericytes and immune cells participate in the biology of these vessels. This microfluidic system will be designed to reproduce the 3- dimensional geometry of capillaries and precisely control their environment.

More informations : Projet microfluidique

A geometry of particular interest concerns flows in a Hele-Shaw cell, i.e. a channel whose depth is much smaller than its width and length. This classical problem has been studied in depth, both theoretically and experimentally [2-4]. While the theoretical solutions predict that the relative velocity of an inviscid bubble should be twice the velocity of the outer fluid, this is never observed in practice. Instead, bubbles travel at lower speeds than the outer fluid. Moreover, complex recirculation patterns are observed for bubbles rising in a quiescent outer fluid [5]. All of these observations point to the effect of an uneven surfactant coverage of the interface and its redistribution due to the fluid motion.

 

Duration: 12 months. For applicants eligible to Eurotalents an extension of at least 6 months should be possible.

Starting date: spring 2016

Localization: LIONS at CEA Saclay, Gif sur Yvette France

Researchers and oncologists see in CSC an explanation as to why cancer may be so difficult to cure. Our project aims at investigating the glycome of breast cancer stem cells, using a combination of transcriptomic, flow-cytometry, glycomic experiments and microfluidics, in order to identify glyco-markers (genes and/or glycans) of stem cells. The function of these glyco-markers in CSC biology will be assessed both in vivo and in vitro using relevant genetically modified cell lines. Particular emphasis is put on the elucidation of CSC-supported metastasis using in-house developed microfluidic devices.

More informations : Advertisement_poste_ingénieur_final

In the context of MAGNEURON, a new project funded through the FET OPEN European program, our group is seeking to recruit a post-doc to join our effort aiming at using magnetic nanoparticles (MNPs) for remote actuation of cell signaling. By means of functionalized MNPs, our goal is to control important cellular processes such as migration, differentiation or division, with the long-term objective of using these approaches in cellbased therapies.

 

More information : Position_LOCCOteam_jan2016

Synergy Microfluidics & Biology

The objective of SYMiBio is to promote scientific exchanges and stimulate interactions between biologists and people of the microfluidics community. This workshop has been initiated by the « Mission pour l’interdisciplinarité du CNRS » and supported by CelTisPhyBio and IPGG Labex, PSL* and the GDR Microfluidique.

SYMiBio is opened to PhD students, post-doctoral fellows and senior scientists.
The program contains a selection of presentations on a wide range biological systems, organized around three pillars illustrating the Microfluidics/Biology synergy : Decipher / Control / Analyze.

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