GDR Micro Nano Fluidique

Mois : novembre 2018

The successful candidate will be expected to carry out the basic duties of this position with a dynamic and creative approach. In particular,
he/she will:
– take part in teaching and in laboratory activities for undergraduate and graduate courses in electrical
– engineering;
– supervise and lead graduate students;
– initiate and carry out leading-edge research projects;
– collaborate with research teams within Polytechnique Montreal and other institutions, notably TransMedTech Institute;
develop and maintain collaborations with industry.

More information : Position_Professor_GE_PolyMTL.pdf

The objective is thus, in the first 12 months period, to investigate the capabilities of such an approach, and eventually obtain a proof of concept based on a simple device. The work is based on a close collaboration between Thales and MMN. The work will be carried out mainly in MMN/IPGG, taking advantage of the facilities and known-how developed locally. Optical calculations will be carried out with the Thales Research and Technology team.

Highly motivated candidates are encouraged from the present to send an application including a CV and a letter of motivation. Applications will be accepted until the position is filled.


This extraction step will be performed using a technology recently pioneered by our team: a microfluidic and magnetic fluidized bed. Fluidized-beds are commonly used to enhance surface interactions in a solid/liquid mixture, with high stirring and low backpressure. Our team developed a completely new concept of micro-fluidized beds based on magnetic micro-particles in equilibrium between flow-induced drag forces and magnetic forces [1]. This system already showed unprecedented efficiency for solid phase extraction and was successfully applied for bacteria analysis [2] and proteins preconcentration [3].

More information : Post-doc-Index-catchU-1.docx

More information : announcement_ERC_PhD_positions.pdf

Context : This PDRA is part of a large project (BEBOP, 2019-2024) funded by the European Research Council. The goal of BEBOP is to figure out how we can use bacteria to control the properties of porous structures (e.g. porosity, permeability). We envision that this will unlock a new generation of biotechnologies, such as self-repairing construction materials or self-cleaning bioreactors. The main scientific obstacle to this technology is the lack of understanding of the biophysical mechanisms associated with the development of bacterial populations within complex porous structures. Therefore, the first scientific objective of BEBOP is to gain insight into how fluid flow, transport phenomena and bacterial communities (biofilms) interact within connected heterogeneous structures. To this end, we will combine microfluidic and 3D printed micro-bioreactor experiments; fluorescence and X-ray imaging; high performance computing bringing together CFD, individual-based models and pore network approaches. The second scientific objective of BEBOP is to create the primary building blocks toward a control theory of bacteria in porous media and to construct a demonstrator bioreactor for permeability control.

More information : BEBOP_PDRA_Microfluidics.pdf

In collaboration with other teams at CEA, the candidate will have to develop and characterize two microfluidic devices for biological entities sorting. The candidate will work on two devices. One to sort in size cell clusters called Langerhans islets involved in the insulin secretion. This task is part of a cell therapy project for type I diabetes aimed at grafting allogenic encapsulated islets to restore glucose regulation with limited or no immuno-suppressive treatments. The other one is related to the sorting of viruses from a plasma sample and their conditioning for subsequent nebulization and detection. It requires both the development and characterization of sorting devices, and their implementation on a fluidic cartridge.

More information : EN_CEA_Post-doctoral-position_Sorting_Bio_Components_09112018.pdf

The project will consist in the development of an autonomous microfluidic oscillator for the continuous determination of nitrate levels by a colorimetric assay. Experimental validation for nitrate quantification will be performed in synthetic and natural waters. The study, development and fabrication of the system will be performed at the LAAS-CNRS, while the laboratory and field validations will be performed in close collaboration with the GET laboratory.

More information : Post-doc-position-2019-OSCILLEAU.pdf

Un des atouts de la nanomédecine est la promesse d’apporter de nouvelles thérapies sur un site, basées sur l’activation à distance de nanomatériaux pour produire par exemple de la chaleur ou des réactions chimiques thérapeutiques, tout en diminuant les effets secondaires. Le défi actuel de ces « nano-thérapies physiques » est d’améliorer leur efficacité thérapeutique. Pour ce faire, une piste moderne est de proposer des nanohybrides qui seraient dotés de plusieurs fonctions thérapeutiques, afin d’amplifier in fine leur potentiel thérapeutique.

Plus d’informations : Sujet-Stage-A-Abou-Hassan-ANR.pdf

Nous recherchons un ingénieur (niveau doctorat ou école d’ingénieur) pour :
– gérer et développer nos stations de microfluidique
– gérer différents projets impliquant la microfluidique
– encadrer et former du personnel sur les appareils

Plus d’informations : offre-emploi-microfluidique_.pdf