Researchers and oncologists see in CSC an explanation as to why cancer may be so difficult to cure. Our project aims at investigating the glycome of breast cancer stem cells, using a combination of transcriptomic, flow-cytometry, glycomic experiments and microfluidics, in order to identify glyco-markers (genes and/or glycans) of stem cells. The function of these glyco-markers in CSC biology will be assessed both in vivo and in vitro using relevant genetically modified cell lines. Particular emphasis is put on the elucidation of CSC-supported metastasis using in-house developed microfluidic devices.

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