This PhD concerns the development of Lab-On-a-Chip systems dedicated to medical diagnosis and drug screening. Indeed, the development of personalized medicine and Point-Of-Care (POC) diagnostic tools addresses a strong social demand related to the steady increase in the number of elderly, and is one of the key issues that the health industry will have to urgently address in near the future. Fluidic microsystems enable the manipulation of small volume of liquids, and thus the reduction of analysis time and cost, while offering enhanced portability. Due to their dimensions, they enable analyses at the single cell level and offer numerous prospects for medical diagnostics and drug screening.

Plus de détails : Thèse INL 2015