PhD – Microsystem to analyze and isolate small population of Leukemia cells with physical phenotype
These cells are (i) the causative agents of late relapse, (ii) refractory to treatments and (iii) leading to relapsing patients poor survival. Deep sequencing by NGS allows identification of these residual cells but their detection is still technically challenging due to lack of phenotypic markers. There is a critical need to find new ways to detect and purify them to anticipate relapse.
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